Ingestion of A Common Plant’s Leaves Leads to Acute Respiratory Arrest and Paralysis: A Case Report
| Autor: | Richard W. Lee, Breelan M. Kear, Anthony Arguija, Sanford B. Church, Fady A. Youssef |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Respiratory arrest
Poison control Case Report nicotinic alkaloids Emergency Nursing Pharmacology Neuromuscular junction chemistry.chemical_compound Nicotiana glauca Paralysis Medicine Ingestion respiratory arrest business.industry fungi lcsh:Medical emergencies. Critical care. Intensive care. First aid toxicity food and beverages Anabasine lcsh:RC86-88.9 medicine.anatomical_structure Nicotinic agonist chemistry Toxicity Emergency Medicine medicine.symptom business |
| Zdroj: | Clinical Practice and Cases in Emergency Medicine Clinical Practice and Cases in Emergency Medicine, Vol 4, Iss 3 (2020) |
| ISSN: | 2474-252X |
| DOI: | 10.5811/cpcem.2020.5.46703 |
| Popis: | Author(s): Kear, Breelan M.; Lee, Richard W.; Church, Sanford B.; Youssef, Fady A.; Arguija, Anthony | Abstract: Background: Nicotiana glauca is a plant known to cause acute toxicity upon ingestion or dermal exposure due to the nicotinic alkaloid, anabasine. Nicotinic alkaloids cause toxicity by acting as agonists on nicotinic-type acetylcholine receptors (nAChRs). Initial stimulation of these receptors leads to symptoms such as tachycardia, miosis, and tremors. The effects of high doses of nicotinic alkaloids are biphasic, and eventual persistent depolarization of nAChRs at the neuromuscular junction occurs. This causes apnea, paralysis, and cardiovascular collapse.Case Report: In this report, we present a case of respiratory arrest due to nicotinic alkaloid poisoning from the ingestion of Nicotiana glauca. The diagnosis was suspected after the patient’s family gave a history of the patient ingesting a plant prior to arrival. They were able to also provide a physical sample of the plant.Conclusion: The phone application, “Plant Snap”, determined the plant species and helped confirm the diagnosis. This case describes how modern technology and thorough history taking can combine to provide the best possible patient care. |
| Databáze: | OpenAIRE |
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