Sequential studies in ankylosing spondylitis. Association of Klebsiella pneumoniae with active disease
| Autor: | D. R. Cawdell, P Cowling, A Ebringer, R Ebringer |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male Klebsiella Time Factors Klebsiella pneumoniae Immunology Disease General Biochemistry Genetics and Molecular Biology Feces Rheumatology Active disease medicine Humans Immunology and Allergy Spondylitis Ankylosing In patient Ankylosing spondylitis biology business.industry biology.organism_classification medicine.disease Klebsiella Infections Positive culture Female Inactive disease business Research Article |
| Zdroj: | Annals of the Rheumatic Diseases. 37:146-151 |
| ISSN: | 0003-4967 |
| DOI: | 10.1136/ard.37.2.146 |
| Popis: | A study of 163 patients with ankylosing spondylitis seen on 433 occasions showed that active inflammatory disease was strongly associated with the presence of Klebsiella pneumoniae in the faeces (P less than 0.001). Sequential studies showed that in patients with inactive disease the presence of a positive culture for Klebsiella was associated with the subsequent development of active inflammatory disease (P less than 0.001). These findings support the hypothesis that Kl. pneumoniae may be an initiating agent in ankylosing spondylitis. |
| Databáze: | OpenAIRE |
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