Anthocyanin Profile and Antioxidant Property of Anti-asthma Flowers of Cordyline terminalis (L.) Kunth (Agavaceae)
| Autor: | Monica Jordheim, Robert Byamukama, Christopher Adaku, Irene Skaar, Øyvind M. Andersen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Pharmacology 0303 health sciences Antioxidant biology 030309 nutrition & dietetics medicine.medical_treatment Plant Science General Medicine Cordyline biology.organism_classification 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Horticulture Complementary and alternative medicine chemistry Anthocyanin Drug Discovery medicine Purple color 010606 plant biology & botany |
| Zdroj: | Natural Product Communications |
| ISSN: | 1555-9475 1934-578X |
| DOI: | 10.1177/1934578x20922637 |
| Popis: | Cordyline terminalis flower is traditionally used to treat asthma and the purple color of the flower is suggestive of anthocyanins. The purpose of this study was to characterize and determine the antioxidant property of anthocyanins from C. terminalis purple flowers. Five anthocyanins, cyanidin 3,5-di- O-β-glucopyranoside (2.6 ± 0.2 mg/g fr. wt) (1), peonidin 3,5-di- O-β-glucopyranoside (2.8 ± 0.3 mg/g fr. wt) (2), cyanidin 3- O-β-(6″- O- E- p-caffeoylglucopyranoside)-5- O-β-glucopyranoside (3.2 ± 0.2 mg/g fr. wt) (3), cyanidin 3- O-β-(6″- O- E- p-coumaroylglucopyranoside)-5- O-β-glucopyranoside (6.2 ± 0.4 mg/g fr. wt) (4), and peonidin 3- O-β-(6″- O- E- p-coumaroylglucopyranoside)-5- O-β-glucopyranoside (9.8 ± 0.2 mg/g fr. wt) (5), were isolated from the flowers of C. terminalis by a combination of chromatographic techniques. Their structures were established by UV-visible, NMR, and ESI-MS. The extract exhibited appreciable antioxidant activity (IC50 ± SD = 13.1 ± 0.8 μg/mL) against quercetin (IC50 ± SD = 4.5 ± 0.4 μg/mL) compared to the individual anthocyanins (IC50 ± SD = 13.8 ± 0.5 to 16.4 ± 0.7 μg/mL) when measured using the 2,2-diphenyl-1-picryl-hydrazyl method. Cordyline terminalis flowers extract may be justified for use and standardization as herbal remedy for asthma. |
| Databáze: | OpenAIRE |
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