Ciprofloxacin-Induced Hemorrhagic Vasculitis
Autor: | J.H.T. Wagenvoort, A.M.J. van der Kleij, Joep A.W. Teijink, Frank P. van den Berg |
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Přispěvatelé: | Epidemiologie, RS: CAPHRI School for Public Health and Primary Care |
Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: |
Male
Staphylococcus aureus medicine.medical_specialty IgA Vasculitis Side effect medicine.medical_treatment Amputation Surgical Gangrene Anti-Infective Agents Ciprofloxacin Enterobacter cloacae Humans Medicine Proteus mirabilis Aged Aged 80 and over Leg business.industry Forefoot General Medicine medicine.disease Dermatology Diabetic Foot Surgery Purpura Amputation Female medicine.symptom Cardiology and Cardiovascular Medicine business Complication Vasculitis medicine.drug |
Zdroj: | Annals of Vascular Surgery, 24(2). Elsevier Science |
ISSN: | 0890-5096 |
Popis: | Ciprofloxacin-induced hemorrhagic vasculitis is a rare side effect. It has only been described in 10 case reports since 1989. However, recently we were confronted with two cases within 1 month. In one patient the vasculitis resolved after termination of the ciprofloxacin therapy; in the other patient the ciprofloxacin-induced hemorrhagic vasculitis was superimposed on a severe forefoot infection, leading to progressive gangrene and a below-knee amputation. Ciprofloxacin is among the standard treatments for infected ischemic ulcers; in the rare case of ciprofloxacin-induced hemorrhagic vasculitis, it might be interpreted as progression of infection, instead of a complication of the treatment, thus leading to faulty diagnosis and treatment. The intention of this case report is to raise awareness for anyone prescribing ciprofloxacin as treatment for infected diabetic and ischemic ulcers. Annals of Vascular Surgery Inc. |
Databáze: | OpenAIRE |
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