Urinary levels of matrix metalloproteinase 9 and 2 and tissue inhibitor of matrix metalloproteinase in patients with coronary artery disease
| Autor: | Hyunsun Kim, M. Hasan Rajab, Reza Forough, A. Michael Spiekerman, Mark E. Lawrence, Patrick J. Fitzsimmons, Brian Weylie, D. Scott Gantt, Gregory J. Dehmer |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Urinary system Coronary Artery Disease Urine Gastroenterology Coronary artery disease Reference Values Internal medicine medicine Humans Myocardial infarction Coronary atherosclerosis Aged Tissue Inhibitor of Metalloproteinase-1 Vascular disease business.industry Middle Aged Tissue inhibitor of metalloproteinase medicine.disease Endocrinology Matrix Metalloproteinase 9 Chemistry Clinical Acute Disease Feasibility Studies Matrix Metalloproteinase 2 Female Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Atherosclerosis. 194:196-203 |
| ISSN: | 0021-9150 |
| Popis: | Objectives: To evaluate the feasibility of an assay for urinary levels of matrix metalloproteinases (MMPs) and the potential usefulness of urinary MMPs as a marker of coronary atherosclerosis or acute coronary syndromes (ACS). Methods and results: We measured urine and plasma MMP-9, MMP-2 and urine tissue inhibitor of metalloproteinase (TIMP-1) in patients with ACS (n = 27), patients with coronary artery disease (CAD), but no clinical instability (n = 47) and a group of healthy volunteers (n = 15) who were |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect