Predictive Factors of Gastrointestinal Injuries after Exposure to Sodium Hypochlorite
| Autor: | Mahdi Rezai, Ahmad Ghoochani Khorasani, Peyman Erfantalab |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Sodium Hypochlorite business.industry Health Toxicology and Mutagenesis Corrosive Poisoning 030232 urology & nephrology Endoscopy 030206 dentistry Bleach Toxicology Gastroenterology Gastrointestinal Injuries 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry lcsh:RA1190-1270 Sodium hypochlorite Internal medicine Medicine business lcsh:Toxicology. Poisons |
| Zdroj: | Iranian Journal of Toxicology, Vol 11, Iss 3, Pp 7-10 (2017) |
| ISSN: | 2251-9459 2008-2967 |
| DOI: | 10.29252/arakmu.11.3.7 |
| Popis: | Background: Sodium hypochlorite is found in bleaching agents used to cleaning dishes and bleach laundry. The ingestion of sodium hypochlorite causes acute corrosive esophagitis and gastritis. In establishing the diagnosis and therapeutic approach of acute corrosive poisonings, the upper endoscopy has great importance. The aim of this study was to determine predictive factors of gastrointestinal injuries that mandate early endoscopy. Methods: This study consisted of 65 patients presented to Loghman Hakim Toxicology Center, Tehran, Iran with history of sodium hypochlorite bleach exposure from 2010 to 2014. The post-corrosive damage classified according to Kikendal’s grading. Results: There were a total of 19 males and 46 females with a mean age of 34.21 yr old. In upper GI endoscopy, 20% of poisoned patients had abnormal findings. Male gender (P=0.029), presence of hoarseness (P=0.044), nausea and vomiting (P=0.007), sialorrhea (P=0.044) and higher age (P=0.05) were associated with the occurrence of gastrointestinal injuries, but only male gender (OR=5.04), nausea and vomiting (OR=8.97) were independent predictors of gastrointestinal injuries (P=0.03 and P=0.03, respectively). Conclusion: We proposed five factors associated with gastrointestinal injuries, which could be important factors that mandate urgent endoscopy. |
| Databáze: | OpenAIRE |
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