Brimonidine for glaucoma
| Autor: | Kanna Ramaesh, Mamun Q. Rahman, Donald M. I. Montgomery |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Intraocular pressure genetic structures Glaucoma Brimonidine Tartrate Quinoxalines Ophthalmology α2 adrenoceptor agonist Animals Humans Medicine Pharmacology (medical) Intensive care medicine Antihypertensive Agents Intraocular Pressure business.industry Brimonidine General Medicine medicine.disease eye diseases Clinical Practice Clinical trial Expert opinion business Adrenergic alpha-Agonists medicine.drug |
| Zdroj: | Expert Opinion on Drug Safety. 9:483-491 |
| ISSN: | 1744-764X 1474-0338 |
| DOI: | 10.1517/14740331003709736 |
| Popis: | Brimonidine is a drug used in the management of glaucoma throughout the world and is the most modern alpha(2)-adrenoceptor agonist available. This review comprehensively discusses the use of brimonidine for glaucoma.A historical insight into the development of selective adrenergic glaucoma drugs is given, followed by a description of the mechanisms of action and a discussion of the main clinical trials investigating clinical applications. The safety of brimonidine is evaluated, and our expert opinion is provided on how brimonidine is used in our clinical practice. The most relevant literature on the role of brimonidine in glaucoma is discussed.A clear understanding of the role of brimonidine for glaucoma treatment, with an explanation of its efficacy, limitations and use in clinical practice.Brimonidine is an effective drug for lowering intraocular pressure. It has potentially serious systemic effects in children, in whom it is contraindicated. Its use in adults is limited by its ocular side effects such as allergy. Brimonidine is, however, an important part of the range of intraocular pressure lowering drugs available to prescribers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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