Performance evaluation of a point of care cartridge of the new GEM Premier ChemSTAT analyzer
| Autor: | Alba E. García-Fernández, Raquel Barquín, Mariano Martínez, Roser Ferrer, Ernesto Casis, Clarke Xu |
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| Přispěvatelé: | Institut Català de la Salut, [García-Fernández AE, Barquín R, Martínez M, Ferrer R, Casis E] Laboratoris Clínics, Vall d'Hebron Hospital Universitari, Barcelona, Spain. [Xu C] Werfen, Bedford, MA, USA, Vall d'Hebron Barcelona Hospital Campus |
| Rok vydání: | 2022 |
| Předmět: |
Otros calificadores::Otros calificadores::/complicaciones [Otros calificadores]
Radiological and Ultrasound Technology Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Azoles::Imidazoles::Creatinine [CHEMICALS AND DRUGS] Ronyons - Malalties - Diagnòstic Clinical Biochemistry Male Urogenital Diseases::Urologic Diseases::Kidney Diseases [DISEASES] Other subheadings::Other subheadings::/blood [Other subheadings] compuestos heterocíclicos::compuestos heterocíclicos de 1 anillo::azoles::imidazoles::creatinina [COMPUESTOS QUÍMICOS Y DROGAS] Creatinina Otros calificadores::Otros calificadores::/sangre [Otros calificadores] enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales [ENFERMEDADES] Ronyons - Malalties - Tractament Other subheadings::Other subheadings::/complications [Other subheadings] |
| Zdroj: | Scientia |
| ISSN: | 2352-5517 |
| DOI: | 10.1016/j.plabm.2022.e00297 |
| Popis: | Acute kidney injury; Creatinine; Point-of-care Lesión renal aguda; Creatinina; Punto de atención Lesió renal aguda; Creatinina; Punt d'atenció Background and aims GEM Premier ChemSTAT is a new point-of-care system providing rapid creatinine, BUN and tCO2 measurements together with electrolytes, metabolites, hematocrit, pH and pCO2 from a single whole blood specimen in acute care settings such as emergency departments and intensive care units. Accurate measurements of whole blood creatinine can aid in the diagnosis and treatment of renal diseases. Materials and methods Heparinized whole blood samples from different clinical locations were evaluated on the GEM Premier ChemSTAT and results compared to plasma from the same samples on the Beckman AU5800 or whole blood on the GEM Premier 4000. Precision studies were conducted with whole blood and quality control material. Results ChemSTAT correlated well with plasma samples on the AU5800 (regression slopes (S): 0.957–1.159, correlation coefficients (r)≥0.952) and with whole blood specimens on the GEM Premier 4000 (S: 0.9646–1.124, r ≥ 0.974). The repeatability was 0.1%–3.1% and QC precision were within lab and manufacturers’ specifications. Conclusion ChemSTAT demonstrated strong correlation to the comparative methods and excellent precision. Combining with its continuous quality management, ChemSTAT is suitable for acute care settings to provide rapid, reliable results, which could minimize time-to-treatment and improve patient outcome. |
| Databáze: | OpenAIRE |
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