Antiphospholipid syndrome characteristics and adverse pregnancy outcomes after 20 weeks of pregnancy
| Autor: | Hadas Zafrir-Danieli, Eran Hadar, Dorit Blickstein, Rinat Gabbay-Benziv, Lina Salman, Anat Shmueli |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty 030204 cardiovascular system & hematology Young Adult 03 medical and health sciences 0302 clinical medicine Pre-Eclampsia Pregnancy Antiphospholipid syndrome medicine Humans Israel Autoantibodies Retrospective Studies Lupus anticoagulant Fetal Growth Retardation 030219 obstetrics & reproductive medicine business.industry Obstetrics Pregnancy-Specific beta 1-Glycoproteins Pregnancy Outcome Antibody titer Autoantibody Obstetrics and Gynecology Retrospective cohort study General Medicine Infant Low Birth Weight Stillbirth Antiphospholipid Syndrome medicine.disease Pregnancy Complications Titer Premature birth Antibodies Anticardiolipin Lupus Coagulation Inhibitor Premature Birth Female business |
| Zdroj: | International Journal of Gynecology & Obstetrics. 142:214-220 |
| ISSN: | 0020-7292 |
| DOI: | 10.1002/ijgo.12511 |
| Popis: | OBJECTIVE To assess outcomes after 20 weeks of pregnancy according to autoantibody profile and clinical presentation of maternal antiphospholipid syndrome (APS). METHODS The present retrospective cohort analysis included women diagnosed with APS at a tertiary medical center in Israel between January 1, 2012, and December 31, 2016. Anticardiolipin antibodies, anti-β2-glycoprotein antibodies, and lupus anticoagulant were assessed. Participants were stratified by type of APS (obstetric vs thrombotic), antibody profile, and antibody titer (low vs high). Primary composite outcomes were rated as severe (stillbirth, fetal growth restriction at |
| Databáze: | OpenAIRE |
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