On the role of metaheuristic optimization in bioinformatics

Autor: Angel A. Juan, Sergio Benito Rey, Ferran Prados Carrasco, Laura Calvet Liñán
Přispěvatelé: Universitat Oberta de Catalunya (UOC), Universitat Politècnica de València
Rok vydání: 2022
Předmět:
Zdroj: O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
ISSN: 1475-3995
0969-6016
DOI: 10.1111/itor.13164
Popis: Metaheuristic algorithms are employed to solve complex and large-scale optimization problems in many different fields, from transportation and smart cities to finance. This paper discusses how metaheuristic algorithms are being applied to solve different optimization problems in the area of bioinformatics. While the text provides references to many optimization problems in the area, it focuses on those that have attracted more interest from the optimization community. Among the problems analyzed, the paper discusses in more detail the molecular docking problem, the protein structure prediction, phylogenetic inference, and different string problems. In addition, references to other relevant optimization problems are also given, including those related to medical imaging or gene selection for classification. From the previous analysis, the paper generates insights on research opportunities for the Operations Research and Computer Science communities in the field of bioinformatics.
Databáze: OpenAIRE