Characteristics of Patients with Chronic Obstructive Pulmonary Disease at the First Visit to a Pulmonary Medical Center in Korea: The KOrea COpd Subgroup Study Team Cohort

Autor: Gyu Rak Chon, Chin Kook Rhee, Sang Haak Lee, Hyoung Kyu Yoon, Ki Suck Jung, Yong Il Hwang, Deog Kyeom Kim, Yong Bum Park, Jin Hwa Lee, Tae Eun Kim, Young Sam Kim, Jung Yeon Lee, Kwang Ha Yoo, Sang Yeub Lee, Tae Hyung Kim
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Questionnaires
Male
Pediatrics
medicine.medical_specialty
Respiratory Diseases
Walk Test
Comorbidity
Severity of Illness Index
Pulmonary function testing
Cohort Studies
Hospitals
University
Tertiary Care Centers
03 medical and health sciences
Pulmonary Disease
Chronic Obstructive
0302 clinical medicine
Forced Expiratory Volume
Surveys and Questionnaires
Severity of illness
Republic of Korea
medicine
Diabetes Mellitus
Humans
030212 general & internal medicine
Lung
Depression (differential diagnoses)
Societies
Medical
Aged
COPD
business.industry
Depression
General Medicine
Middle Aged
medicine.disease
Obstructive lung disease
respiratory tract diseases
Respiratory Function Tests
Dyspnea
030228 respiratory system
Cohort
Hypertension
Quality of Life
Original Article
Female
business
Cohort study
Zdroj: Journal of Korean Medical Science
ISSN: 1598-6357
1011-8934
Popis: The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and university-affiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George’s Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean post-bronchodilator FEV1 was 55.8% ± 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies.
Graphical Abstract
Databáze: OpenAIRE
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