Design of selective Cathepsin inhibitors

Autor:	Stefan Gerhardt, Andrew David Morley, Peter W. Kenny, Hannes Simader, Emma V. Jones, Galith Karoutchi, Stephan Krapp, Neil Rankine, Keith Oldham, Paul A. Bethel, Stefan Steinbacher, Martin Augustin
Rok vydání:	2009
Předmět:	Cathepsin biology Chemistry Organic Chemistry Clinical Biochemistry Pharmaceutical Science Crystallography X-Ray Cathepsins Biochemistry Cathepsin B Cathepsin L Structure-Activity Relationship Molecular recognition Drug Design Drug Discovery Cathepsin L2 Cathepsin K biology.protein Molecular Medicine Computer Simulation Protease Inhibitors Cathepsin V Molecular Biology Cathepsin S
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 19:4622-4625
ISSN:	0960-894X
Popis:	A number of molecular recognition features have been exploited in structure-based design of selective Cathepsin inhibitors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5e987a8e0f4a810fd0d5bfae2d2508 https://doi.org/10.1016/j.bmcl.2009.06.090 Zobrazit plný text záznamu Full Text from ScienceDirect