Anti-tumor alkaloids from Peganum harmala

Autor: Qin, Zhang, Yan-Hui, Zan, Han-Gao, Yang, Meng-Yue, Yang, Fang-Shen, Liu, Sheng-Ge, Li, Xiao-Hui, Peng, Bin, Lin, Zhan-Lin, Li, Da-Hong, Li, Hui-Ming, Hua
Rok vydání: 2022
Předmět:
Zdroj: Phytochemistry. 197:113107
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2022.113107
Popis: Six alkaloids peharmalines F-K, along with 14 known ones, were isolated from the aerial part of Peganum harmala L.. The structures of the isolated compounds were determined based on their HR-ESI-MS data, extensive NMR spectroscopic analyses, and ECD calculations. 3-(4-Hydroxyphenyl)quinoline exhibited potent antiproliferative activity against the HepG-2 cell lines with an IC
Databáze: OpenAIRE