Potentiometric investigation of the stability of palladium(II) complex of pralidoxime chloride in aqueous solution
| Autor: | K. Karljiković-Rajić, B. Stanković |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
acidic constant
Clinical Biochemistry Inorganic chemistry Potentiometric titration Pharmaceutical Science chemistry.chemical_element 010402 general chemistry 01 natural sciences Chloride palladium(II) complex Analytical Chemistry Drug Stability Drug Discovery medicine Sodium Hydroxide Spectroscopy Pralidoxime chloride Pralidoxime Compounds Aqueous solution 010405 organic chemistry Hydrogen-Ion Concentration stability constant 0104 chemical sciences Solutions Kinetics chemistry Ionic strength Stability constants of complexes Potentiometry Indicators and Reagents potentiometric determination Constant (mathematics) Palladium medicine.drug |
| Zdroj: | Journal of Pharmaceutical and Biomedical Analysis |
| ISSN: | 0731-7085 |
| Popis: | The formation of a complex between palladium(II) chloride and pralidoxime chloride (PAM-2Cl) has been studied by means of potentiometric pH measurements. The real stability constant of the complex in aqueous medium of ionic strength 0.3 M (KCl) at 25.0°C was log K s = 7.29. This value was close to that (log K s = 7.02) obtained previously by spectrophotometric methods after appropriate correction with respect to the corresponding value of the acidic constant of PAM-2Cl (p K c a = 8.05), which was also determined under the same experimental conditions. |
| Databáze: | OpenAIRE |
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