The clinical relevance of Organ Procurement and Transplantation Network screening criteria for program performance review in the United States
| Autor: | Bertram L. Kasiske, Andrew Wey, Nicholas Salkowski, Jon J. Snyder, Ajay K. Israni, Jeffrey P. Orlowski |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Tissue and Organ Procurement education 030230 surgery Organ transplantation Donor Selection 03 medical and health sciences 0302 clinical medicine medicine Humans Clinical significance Registries Intensive care medicine Retrospective Studies Transplantation Donor selection business.industry Graft Survival Retrospective cohort study Organ Transplantation Prognosis Tissue Donors Transplant Recipients United States Organ procurement surgical procedures operative Cohort Female 030211 gastroenterology & hepatology Graft survival business Follow-Up Studies |
| Zdroj: | Clinical Transplantation. 30:1066-1073 |
| ISSN: | 0902-0063 |
| DOI: | 10.1111/ctr.12789 |
| Popis: | The Organ Procurement and Transplantation Network is charged with overseeing the quality of transplant programs in the United States. However, there has been controversy over whether too many programs are being identified as underperforming. It has also been suggested that dramatic improvements in outcomes throughout the United States have made the thresholds for determining which deceased donor transplant programs are underperforming no longer clinically relevant. The Scientific Registry of Transplant Recipients compared actual and expected 1-y graft survival for transplant programs identified as underperforming in the most recent cohort (transplants from July 1, 2012 to December 31, 2014). For most organs, actual 1-y graft survival was substantially lower for programs identified as underperforming than for programs identified as performing as expected. Differences were smallest for kidney programs: median 1-y graft survival 89.2% vs 95.4% in large-volume programs identified and not identified for Membership and Professional Standards Committee review, respectively. Median expected graft survival was only slightly lower (94.8% vs 95.1%, respectively), suggesting that identified and not identified programs tend to have similar risk tolerances. An excess of 143 grafts were lost from kidney programs identified as underperforming. Transplant programs identified as underperforming generally have reduced 1-y graft survival that stakeholders may consider clinically relevant. |
| Databáze: | OpenAIRE |
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