Cholesterol-lowering effects of dietary fiber: a meta-analysis
| Autor: | Lisa E. Brown, W Willett, Frank M. Sacks, Bernard Rosner |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Dietary Fiber medicine.medical_specialty food.ingredient Pectin Guar Medicine (miscellaneous) Blood lipids chemistry.chemical_compound food Internal medicine Mole medicine Humans Food science Least-Squares Analysis Triglycerides Aged Analysis of Variance Nutrition and Dietetics Guar gum Chemistry Cholesterol Cholesterol LDL Middle Aged Psyllium Endocrinology lipids (amino acids peptides and proteins) Controlled Clinical Trials as Topic Quantitative analysis (chemistry) medicine.drug |
| Zdroj: | The American Journal of Clinical Nutrition. 69:30-42 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/69.1.30 |
| Popis: | Background: The effects of dietary soluble fibers on blood cholesterol are uncertain. Objective: This meta-analysis of 67 controlled trials was performed to quantify the cholesterol-lowering effect of major dietary fibers. Design: Least-squares regression analyses were used to test the effect on blood lipids of pectin, oat bran, guar gum, and psyllium. Independent variables were type and amount of soluble fiber, initial cholesterol concentration, and other important study characteristics. Results: Soluble fiber, 2‐10 g/d, was associated with small but significant decreases in total cholesterol [ 20.045 mmol · L 21 ·g soluble fiber 21 (95% CI: 20.054, 20.035)] and LDL cholesterol [20.057 mmol · L 21 ·g 21 (95% CI: 20.070, 20.044)]. The effects on plasma lipids of soluble fiber from oat, psyllium, or pectin were not significantly different. We were unable to compare effects of guar because of the limited number of studies using 2‐10 g/d. Triacylglycerols and HDL cholesterol were not significantly influenced by soluble fiber. Lipid changes were independent of study design, treatment length, and background dietary fat content. Conclusions: Various soluble fibers reduce total and LDL cholesterol by similar amounts. The effect is small within the practical range of intake. For example, 3 g soluble fiber from oats (3 servings of oatmeal, 28 g each) can decrease total and LDL cholesterol by |
| Databáze: | OpenAIRE |
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