A comparative study of vascular injection fluids in fresh-frozen and embalmed human cadaver forearms
| Autor: | Jan G. M. Kooloos, Tamas Kozicz, Michel M.P.J. Reijnen, Rombout R. Kruse, Denise E. Doomernik |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Histology Latex Silicones Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] Other Research Donders Center for Medical Neuroscience [Radboudumc 0] 03 medical and health sciences chemistry.chemical_compound Silicone Forearm Cadaver Infusion Procedure Paint medicine Humans Molecular Biology Ecology Evolution Behavior and Systematics Embalming Epoxy Resins business.industry Dissection Soft tissue Original Articles Cell Biology Penetration (firestop) Arterial tree Surgery medicine.anatomical_structure chemistry Blood Vessels Gelatin 030101 anatomy & morphology Anatomy business Plastics Developmental Biology Subcutaneous tissue Biomedical engineering |
| Zdroj: | Journal of Anatomy, 229, 4, pp. 582-90 Journal of Anatomy, 229, 582-90 |
| ISSN: | 0021-8782 |
| Popis: | Contains fulltext : 167684.pdf (Publisher’s version ) (Closed access) Over the years, various vascular injection products have been developed to facilitate anatomical dissections. This study aimed to compare the most commonly used vascular injection products in fresh-frozen and formalin-embalmed cadaver specimens. An overview of the properties, advantages and limitations of each substance was given, and a comparison of vascular infusion procedures in both preservation methods was made. A literature search was performed in order to identify the most commonly used vascular injection products. Acrylic paint, latex, gelatin, silicone, Araldite F and Batson's No. 17 were selected for the study. One fresh-frozen and one embalmed cadaver forearm were infused with each injection product according to a uniform protocol. The curing time, skin- and subcutaneous tissue penetration, degree of filling of the arterial tree, extravasations, consistency of the injected vessels during dissection, and the costs of each injection fluid were noted. There was a large variation between the injection fluids in processing- and curing time, colour intensity, flexibility, fragility, elasticity, strength, toxicity and costs. All fluids were suitable for infusion. The penetration of injection fluid into the skin and subcutaneous tissue was significantly better in fresh-frozen specimens (P = 0.002 and P = 0.009, respectively), with significantly smaller branches casted (P = 0.004). Vascular infusion of fresh-frozen cadaver specimens results in a significantly better filled coloured arterial tree, enabling more detail to be achieved and smaller branches casted. The biomechanical properties of fresh-frozen soft tissues are less affected compared with formalin fixation. All the injection fluids studied are suitable for vascular infusion, but their different properties ensure that certain products and procedures are more suitable for specific study purposes. |
| Databáze: | OpenAIRE |
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