Seroprevalence of Cryptosporidial Antibodies During Infancy, Childhood, and Adolescence
| Autor: | Judy Griffis, Derek A. Mosier, David L. Crawford, Thomas L. Kuhls |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Diarrhea
Male Rural Population Microbiology (medical) Adolescent Urban Population Antibodies Protozoan Cryptosporidiosis Enzyme-Linked Immunosorbent Assay Age groups Seroepidemiologic Studies Ethnicity Prevalence medicine Animals Humans Seroprevalence Risk factor Child Socioeconomic status Cryptosporidium parvum biology business.industry Age Factors Infant Oklahoma Child Day Care Centers biology.organism_classification Infectious Diseases Socioeconomic Factors El Niño Child Preschool Diarrhea Infantile Immunology biology.protein Female Antibody medicine.symptom business Demography |
| Zdroj: | Clinical Infectious Diseases. 18:731-735 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/clinids/18.5.731 |
| Popis: | Cryptosporidium parvum causes mild to moderately severe diarrhea in immunocompetent individuals. Cryptosporidial antibodies in the sera of 803 children seen at Children's Hospital of Oklahoma were measured by means of an ELISA. Thirteen percent of children younger than 5 years of age were seropositive for antibodies to C. parvum. The seropositivity rate for children who attended day-care facilities was higher than that for those who did not. In addition, children in this age group with a history of recent diarrhea were seropositive at a higher rate than were children without diarrhea. Thirty-eight percent of children (5-13 years of age) and 58% of adolescents (14-21 years of age) were seropositive for antibodies to C. parvum. Blacks and Native Americans in these age groups had higher seropositivity rates than did White non-Hispanics. There were no differences in seropositivity rates between sexes or between residents of the largest urban counties in Oklahoma and residents of the more rural counties. Exposure to C. parvum during childhood is common in Oklahoma. Socioeconomic factors may play a role in early exposure to this protozoal pathogen. |
| Databáze: | OpenAIRE |
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