Skin-Sparing Mastectomy and Immediate Breast Reconstruction in the Management of Locally Recurrent Breast Cancer

Autor: K. von Smitten, Tuomo J. Meretoja, Tiina Jahkola, Andrew Lindford
Rok vydání: 2010
Předmět:
Zdroj: Annals of Surgical Oncology. 17:1669-1674
ISSN: 1534-4681
1068-9265
DOI: 10.1245/s10434-010-0957-8
Popis: To investigate whether skin-sparing mastectomy (SSM) and immediate breast reconstruction (IBR) is a possible treatment option in selected cases of locally recurrent breast cancer after previous breast-conserving therapy (BCT).Sixty consecutive patients were treated by SSM and IBR between 1995 and 2008 for ipsilateral breast tumour recurrence (IBTR). Selection criteria consisted of: IBTR3 cm size, not infiltrating skin or chest wall, primarily node negative, recurrence3 years after primary operation, and no metastases. Patient records were analysed retrospectively and follow-up data on patient outcome included.The reconstruction method consisted of 40 free abdominal flaps, 18 latissimus dorsi (LD) flaps with or without an implant, and two cases of implant only. Twenty-three patients received adjuvant oncological therapy. During median follow-up of 66 months, 11 patients (18%) developed disease relapse, including 6 (10%) local re-recurrences.IBR is a possible treatment option for patients who develop local recurrence following earlier BCT. Our local re-recurrence rate of 10% compares well with that following salvage mastectomy for IBTR. Of patients, 43% did not actually meet our selection criteria but yet appeared to fare well in terms of outcome. Therefore we should re-evaluate our selection criteria.
Databáze: OpenAIRE