Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study

Autor: Chang-Wook Min, Gab Jin Cheon, Young Seok Kim, Sae Hwan Lee, Young Chang, Young Don Kim, Dae-Sung Kyoung, Baek Gyu Jun, Hong Soo Kim, Jeong-Ju Yoo, Min-Ae Park, Soung Won Jeong, Jae Young Jang, Hyun Ho Jo, Sang Gyune Kim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Liver Cirrhosis
Male
Cardiothoracic Surgery
Cirrhosis
Epidemiology
Orthopedic Surgery
law.invention
0302 clinical medicine
Risk Factors
law
Medicine and Health Sciences
Medicine
Anesthesia
Hospital Mortality
Multidisciplinary
Liver Diseases
Mortality rate
Middle Aged
Prognosis
Intensive care unit
Intensive Care Units
Plastic surgery
Liver
030220 oncology & carcinogenesis
Female
030211 gastroenterology & hepatology
Plastic Surgery and Reconstructive Techniques
Research Article
medicine.medical_specialty
Death Rates
Science
Surgical and Invasive Medical Procedures
Gastroenterology and Hepatology
Risk Assessment
03 medical and health sciences
Musculoskeletal System Procedures
Population Metrics
Internal medicine
Republic of Korea
Humans
Decompensation
Mortality
Aged
Population Biology
business.industry
Biology and Life Sciences
Postoperative complication
Length of Stay
medicine.disease
Otolaryngological Procedures
Otorhinolaryngology
Medical Risk Factors
business
Varices
Zdroj: PLoS ONE, Vol 16, Iss 6, p e0253165 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Background Patients with liver cirrhosis have an increased risk of in-hospital mortality or postoperative complication after surgery. However, large-scale studies on the prognosis of these patients after surgery are lacking. The aim of the study was to investigate the adverse outcomes of patients with liver cirrhosis after surgery over five years. Methods and findings We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56–1.79, P Conclusion The adverse outcomes of patients with cirrhosis is significantly high after surgery, despite advances in cirrhosis treatment.
Databáze: OpenAIRE
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