RADIOGRAPHIC BONE LOSS CORRELATIONS AND TECHNETIUM-99m-MDP BONE UPTAKE IN LIGATURE-INDUCED PERIODONTAL DISEASE IN THE BEAGLE
| Autor: | Jeffcoat Mk, Boring Jg, Merrilee Holland, Pickrum Hm, Boyle Cr |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Alveolar Bone Loss Dentistry Mandible Technetium Tc 99m Medronate Beagle Bone resorption Dogs Periodontal Attachment Loss Alveolar Process Premolar medicine Animals Bicuspid Radionuclide Imaging Ligature Ligation Periodontal Diseases Dental alveolus General Veterinary business.industry Alveolar process Soft diet Gingival Crevicular Fluid Diet Surgery Radiography Disease Models Animal medicine.anatomical_structure Clinical attachment loss Acute Disease Chronic Disease Disease Progression Prostaglandins Female Periodontal Index Radiopharmaceuticals business |
| Zdroj: | Veterinary Radiology Ultrasound. 39:366-374 |
| ISSN: | 1740-8261 1058-8183 |
| Popis: | The goal of this study was to develop an animal model for the study of acute periodontal disease using silk ligatures in combination with a soft diet in eleven purebred beagle dogs. The silk ligatures were placed subgingivally on the mandible second and fourth premolar on one side of the mouth; the opposite side served as a control. Dogs were monitored during the 16-20 weeks of ligature placement, and for 48 weeks after ligature removal. Development of periodontal disease was evaluated by radiopharmaceutical uptake into bone, radiographic evidence of alveolar bone loss, attachment loss, gingival index and prostaglandin level. Bone loss occurred on the ligatured side during the ligature phase of the study. Radiopharmaceutical uptake was correlated with radiographic evidence of bone loss during the ligature phase. No significant bone loss occurred during the post-ligature phase. Progressive periodontal disease was induced during ligature placement. However, a chronic less aggressive form was not sustained by soft diet alone after ligature removal. |
| Databáze: | OpenAIRE |
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