Sestamibi SPECT scintigraphy for detection of postoperative hyperfunctional parathyroid glands
| Autor: | T M Simonson, M. E. Schurrer, J E Seabold, N J Gurll |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Surgical results
Adenoma Technetium Tc 99m Sestamibi medicine.medical_specialty Scintigraphy Parathyroid Glands Recurrence medicine Humans Radiology Nuclear Medicine and imaging In patient Tomography Emission-Computed Single-Photon Hyperparathyroidism Hyperplasia medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Parathyroid Neoplasms Hypercalcemia Operative time Female Radiology Detection rate business Nuclear medicine Emission computed tomography |
| Zdroj: | AJR. American journal of roentgenology. 166(6) |
| ISSN: | 0361-803X |
| Popis: | Preoperative localization of residual diseased panathyroid glands is essential to improving surgical results in patients with persistent or recurrent hypenpanathynoidism. Moreover, 62-75% of the residual hypenfunctional glands are located in aberrant sites outside the neck [1]. Suboptimal detection rates ranging from 40% to 82% have been reported for vanoustechniques [1-3]. Postoperative anatomic alterations make it difficult to detect residual hyperfunctional panathynoid glands by most anatomic imaging techniques. Planar sestamibi ( ‘Tc-methoxyisobutyl-isonitnile [MIBI]) scintignaphy has shown better results than 201fl n gna phy in the initial evaluation of hypenpanathyroidism [3]. Further, planan Tc-MlBl scintigraphy has been successfully used to locate persistent hypenlunctional panathynoid glands in patients who have undergone prior neck explorations for hypenpanathynoidism [3, 4]. Most persistent lesions are in aberrant locations where ‘ TcMIBI single-photon emission computed tomography (SPECT) scmntignaphy should afford more precise anatomic localization than is afforded by planar scintignaphy. SPECT is superior to planar scmntigraphy and reduces operative time in patients with primary hypenpanathynoidism [5], but there have been no reports of SPECT results in patients with persistent on recurrent hypenparathynoidism to our knowledge. We report the use of Tc-MIBI SPECT in conjunction with planar scintignaphy, which allowed better anatomic localization of residual aberrant hypenfunctional panathynoid glands (either glands that had an adenoma on that were hyperplastic) in two patients with persistent postoperative hypencalcemia |
| Databáze: | OpenAIRE |
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