Seroprevalence of hepatitis B virus infection, anti-HCV antibodies and HIV and knowledge among people who use drugs attending methadone therapy clinic in Tanzania; a cross-sectional study

Autor:	Grahame Mtui, Semvua B. Kilonzo, Paulina M. Manyiri, Daniel W. Gunda, Fredrick Kalokola, Elichilia R. Shao, Fatma A. Bakshi, Hyasinta Jaka, Alex Stephano, David C. Majinge
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Adult Male Health Knowledge Attitudes Practice medicine.medical_specialty Adolescent Methadone clinic Cross-sectional study HIV Infections Infectious and parasitic diseases RC109-216 medicine.disease_cause Ambulatory Care Facilities Tanzania Drug Users Young Adult 03 medical and health sciences 0302 clinical medicine Medical microbiology Seroepidemiologic Studies Internal medicine medicine Humans Seroprevalence 030212 general & internal medicine Viral hepatitis Retrospective Studies Hepatitis B virus 0303 health sciences 030306 microbiology business.industry Transmission (medicine) HIV Hepatitis C Antibodies Middle Aged Hepatitis B medicine.disease Hepatitis C Cross-Sectional Studies Infectious Diseases Female business People who use drugs Methadone Research Article medicine.drug
Zdroj:	BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021) BMC Infectious Diseases
ISSN:	1471-2334
Popis:	Background Methadone therapy clinics have been recently introduced in Tanzania, aiming at reducing risk behaviors and infection rates of viral hepatitis and HIV among people who use drugs. The objective of this study was to estimate the prevalence, associated factors and knowledge level of these conditions among people who use drugs attending a methadone clinic in Tanzania. Methods We enrolled 253 People who using drugs receiving Methadone therapy. Clinical data was retrospectively collected from the medical records and face-to face interviews were conducted to determine the behavioral risk factors and respondents’ knowledge on viral hepatitis and HIV. Results An overall seroprevalence of viral hepatitis (either hepatitis B surface antigen or anti-hepatitis C virus) was 6.3%, while that of hepatitis B virus mono infection was 3.5% and anti-hepatitis C antibodies was 3.5%. Seroprevalence of HIV was 12.6%. Viral hepatitis was strongly predicted by advanced age (> 35 years) (p = 0.02) and staying at Kirumba area (p = 0.004), and HIV infection was predicted by increased age (> 37 years) (p = 0.04) and female sex (p p = 0.001). Conclusions Despite the efforts to curb viral hepatitis and HIV infections through Methadone clinics, infection rates among people who use drugs are still high and the general knowledge on preventive measures is inadequate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5865763f412b6948248b3a8c61cfca07 https://doaj.org/article/9c8daa2c0ead4a76979cf8cf246f3b33 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.