Structural characterisation and anti-ageing activity of extracellular polysaccharide from a strain of Lachnum sp
| Autor: | Jing-min Cai, Wu-xi Chen, Ru-yue Yuan, Ming Ye, Tao Qiu, Ying-wang Ye |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Aging
Antioxidant medicine.medical_treatment education Polysaccharide Antioxidants Analytical Chemistry Superoxide dismutase Mice Polysaccharides medicine Lachnum Animals health care economics and organizations Glucan chemistry.chemical_classification biology Molecular Structure Glutathione peroxidase Glycosidic bond General Medicine biology.organism_classification chemistry Biochemistry Catalase biology.protein Oxidation-Reduction hormones hormone substitutes and hormone antagonists Food Science |
| Zdroj: | Food chemistry. 132(1) |
| ISSN: | 1873-7072 |
| Popis: | A homogeneous extracellular polysaccharide of Lachnum YM261(LEPS-1) with a molecular weight of 21670Da was characterised. According to HPGPC, IR, periodate oxidation and Smith degradation, GC-MS and (1)H NMR analysis, the results indicated that LEPS-1 was a glucan linked by the β-(1→3)-d-pyran glycosidic bond. The effect of LEPS-1 on anti-ageing in d-gal model mice was also studied. It was found that LEPS-1 significantly increased the activities of antioxidant enzymes (i.e. SOD superoxide dismutase, CAT catalase, GSH-PX glutathione peroxidase) and decreased malondialdehyde (MDA) content in liver, brain and serum of d-gal model mice. These results showed that LEPS-1 had a strong anti-ageing activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect