A comprehensive database for the small nucleolar RNAs from Saccharomyces cerevisiae
Autor: | Dmitry Samarsky, Maurille J. Fournier |
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Rok vydání: | 1999 |
Předmět: |
Databases
Factual Genes Fungal Saccharomyces cerevisiae Information Storage and Retrieval Ribosome biogenesis computer.software_genre Genome RNA Small Nuclear Genetics Small nucleolar RNA Genomic organization Internet Database biology urogenital system Fungal genetics RNA Fungal Ribosomal RNA biology.organism_classification GenBank Database Management Systems computer Cell Nucleolus Research Article |
Zdroj: | Nucleic Acids Research. 27:161-164 |
ISSN: | 1362-4962 0305-1048 |
DOI: | 10.1093/nar/27.1.161 |
Popis: | Small nucleolar RNAs (snoRNAs) are involved in cleavage of rRNA, modification of rRNA nucleotides and, perhaps, other aspects of ribosome biogenesis in eukaryotic cells. Scores of snoRNAs have been discovered in recent years from various eukaryotes, and the total number is predicted to be up to 200 different snoRNA species per individual organism. We have created a comprehensive database for snoRNAs from the yeast Saccharomyces cerevisiae which allows easy access to detailed information about each species known (almost 70 snoRNAs are featured). The database consists of three major parts: (i) a utilities section; (ii) a master table; and (iii) a collection of tables for the individual snoRNAs. The utilities section provides an introduction to the database. The master table lists all known S. cerevisiae snoRNAs and their major properties. Information in the individual tables includes: alternate names, size, family classification, genomic organization, sequences (with major features identified), GenBank accession numbers, occurrence of homologues, gene disruption phenotypes, functional properties and associated RNAs and proteins. All information is accompanied with appropriate literature references. The database is available on the World Wide Web (http://www.bio.umass. edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_ DataBase.html), and should be useful for a wide range of snoRNA studies. |
Databáze: | OpenAIRE |
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