The Dissimilar Impact in Atrial Substrate Modification of Left and Right Pulmonary Veins Isolation after Catheter Ablation of Paroxysmal Atrial Fibrillation

Autor: Aikaterini Vraka, Vicente Bertomeu-González, Lorenzo Fácila, José Moreno-Arribas, Raúl Alcaraz, José J. Rieta
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Personalized Medicine; Volume 12; Issue 3; Pages: 462
ISSN: 2017-8395
Popis: [EN] Since the discovery of pulmonary veins (PVs) as foci of atrial fibrillation (AF), the commonest cardiac arrhythmia, investigation revolves around PVs catheter ablation (CA) results. Notwith-standing, CA process itself is rather neglected. We aim to decompose crucial CA steps: coronary sinus (CS) catheterization and the impact of left and right PVs isolation (LPVI, RPVI), separately. We recruited 40 paroxysmal AF patients undergoing first-time CA and obtained five-minute lead II and bipolar CS recordings during sinus rhythm (SR) before CA (B), after LPVI (L) and after RPVI (R). Among others, duration, amplitude and atrial-rate variability (ARV) were calculated for P-waves and CS local activation waves (LAWs). LAWs features were compared among CS channels for reliability analysis. P-waves and LAWs features were compared after each ablation step (B, L, R). CS channels: amplitude and area were different between distal/medial (p = 93%) than distal (+73.12%, p
This research has received partial financial support from public grants DPI2017-83952-C3, PID2021-00X128525-IV0, PID2021-123804OB-I00 and TED2021-129996B-I00 of the Spanish Government 10.13039/501100011033 jointly with the European Regional Development Fund (EU), SBPLY/17/180501/000411 from Junta de Comunidades de Castilla-La Mancha and AICO/2021/286 from Generalitat Valenciana.
Databáze: OpenAIRE