Pulmonary arterial hypertension in the elderly population
| Autor: | Chang-Ying Chen, Shu-Hung Kuo, Fu-Ting Tsai, Yun-Ju Fu, Wei-Chun Huang, Wan-Ting Hung, Cheng-Hung Chiang, Hsiao-Yun Tai, Chia-Lin Wang, Yi-Ching Tsa, Kun-Chang Lin, Cheng Chung Hung |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Treatment response Population Disease Internal medicine Elderly population polycyclic compounds medicine Humans Registries Young female education Aged education.field_of_study Pulmonary Arterial Hypertension business.industry Diastolic heart failure General Medicine Middle Aged medicine.disease Pulmonary hypertension humanities United Kingdom Female business Combination drug |
| Zdroj: | Journal of the Chinese Medical Association : JCMA. 85(1) |
| ISSN: | 1728-7731 |
| Popis: | Pulmonary arterial hypertension (PAH) was a disease predominantly affecting young females about 40 years ago; however, it has been increasingly diagnosed in elderly individuals. Few studies have investigated the features of elderly patients with PAH. This review provides an overview of the characteristics of elderly patients with PAH compared to young patients. The examination of the changing demographics of the population with PAH revealed that the mean age has increased over the years. In addition, the investigation into the diagnostic challenges in elderly patients with PAH revealed the difficulty in differentiating PAH from pulmonary hypertension secondary to diastolic heart failure. Moreover, it was noted that elderly patients underwent combination drug regimens less frequently and exhibited poorer treatment responses than young patients. Finally, it was found that elderly PAH patients experienced poorer survival than young patients. The differences among five survival prediction models and their applicability in predicting the prognosis of PAH patients are discussed. |
| Databáze: | OpenAIRE |
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