Forearm bone mass predicts mortality in chronic hemodialysis patients

Autor: Lidija Orlić, Josipa Josipović, Zeljka Crncevic-Orlic, Ivan Jakopčić, Draško Pavlović, Ivana Mikolašević
Rok vydání: 2016
Předmět:
Adult
Male
medicine.medical_specialty
Survival
Bone density
Endocrinology
Diabetes and Metabolism
medicine.medical_treatment
030232 urology & nephrology
030209 endocrinology & metabolism
Kaplan-Meier Estimate
Standard score
Bone and Bones
03 medical and health sciences
0302 clinical medicine
Endocrinology
Forearm
Bone Density
Renal Dialysis
Risk Factors
Z-scores
Cause of Death
Internal medicine
Bone mineral density
medicine
Humans
Orthopedics and Sports Medicine
Mortality
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine
Aged
Demography
Aged
80 and over
BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina
Bone mineral
Trochanter
business.industry
Mortality rate
Organ Size
General Medicine
Middle Aged
Surgery
medicine.anatomical_structure
Orthopedic surgery
Cardiology
Female
Hemodialysis
Chronic hemodialysis
business
Zdroj: Journal of Bone and Mineral Metabolism
Volume 35
Issue 4
ISSN: 1435-5604
0914-8779
DOI: 10.1007/s00774-016-0766-7
Popis: We aim to determine the relationship between bone mineral density (BMD), measured by T- and Z-score, and mortality risk in hemodialysis (HD) patients. We also investigate which are the most suitable skeletal sites for predicting mortality rate. We analyzed the survival of 102 patients who had been treated with chronic HD according to BMD. Patients with a T-score ≤2.5 at the middle, ultradistal and proximal part of the forearm had a higher mortality risk than those with a T-score of -2.5 or higher. Furthermore, no statistically significant association was found between loss of bone mass at other measuring points-lumbar spine (anteroposterior orientation from L1-L4) and hip (neck, trochanter, intertrochanter, total and Ward's triangle)-and mortality risk. We were also interested in exploring the relationship between Z-score at different skeletal regions and mortality risk. We found that patients with a Z-score of -1 or lower at all three parts of the forearm had a greater mortality risk. It is also worth noting that the Z-score at all three parts of the forearm was a more apparent predictor of mortality, compared to the T-score at the same skeletal regions. This empirical analysis showed that BMD assessments should be obtained at the forearm, due to the good predictability of this skeletal site regarding mortality of HD patients. Moreover, data concerning bone density should be reported as Z-scores.
Databáze: OpenAIRE
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