Complete remission of Sweet’s syndrome after azacytidine treatment for concomitant myelodysplastic syndrome

Autor: Enrico Lista, Gian Matteo Rigolin, Giulia Daghia, Antonio Cuneo, Francesca Cibien, Olga Sofritti, Roberta Gafà, Sara Martinelli, Genesio Leo, Francesco Cavazzini
Rok vydání: 2014
Předmět:
Zdroj: International Journal of Hematology. 99:663-667
ISSN: 1865-3774
0925-5710
DOI: 10.1007/s12185-014-1527-9
Popis: Sweet's syndrome is a rare condition with potentially disabling implications, characterized by painful skin lesions due to neutrophilic dermal infiltration and systemic inflammatory symptoms. A significant proportion of cases is malignancy associated. Hematologic neoplasms, particularly acute myeloid leukemia and myelodysplastic syndromes, are the most commonly associated malignant conditions. Here, we describe the first case of clinical remission of refractory Sweet's syndrome following hypomethylating therapy with azacytidine in a patient with myelodysplastic syndrome who concurrently obtained a complete hematologic response.
Databáze: OpenAIRE