Diabetes mellitus does not preclude stabilization or improvement of renal function after stent revascularization in patients with kidney insufficiency and renal artery stenosis
| Autor: | Stephen R. Ramee, Christopher J. White, Tyrone J. Collins, Rajesh Subramanian, J. Stephen Jenkins, Jose A. Silva, Srinivas Potluri |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Renal function Blood Pressure Kidney Kidney Function Tests Renal Artery Obstruction urologic and male genital diseases Revascularization Renal artery stenosis Severity of Illness Index chemistry.chemical_compound Ischemia Internal medicine medicine.artery Azotemia medicine Humans Diabetic Nephropathies Radiology Nuclear Medicine and imaging Renal Insufficiency Chronic Renal artery Aged Retrospective Studies Creatinine Renal ischemia business.industry Stent General Medicine medicine.disease Treatment Outcome medicine.anatomical_structure chemistry Research Design Cardiology Female Stents Cardiology and Cardiovascular Medicine business Vascular Surgical Procedures Follow-Up Studies |
| Zdroj: | Catheterization and Cardiovascular Interventions. 69:902-907 |
| ISSN: | 1522-726X 1522-1946 |
| DOI: | 10.1002/ccd.20980 |
| Popis: | Objective: To assess the impact of stent revascularization on the renal function of diabetic and nondiabetic patients with renal insufficiency. Background: Renal artery revascularization has been shown to stabilize or improve renal function in patients with significant renal artery stenosis and impaired renal function. However, some studies have suggested negligible or no benefit of renal function in diabetic patients with the same condition. Methods: We retrospectively compared data from 50 consecutive patients undergoing renal artery stent placement with renal insufficiency (serum creatinine ≥1.5–4.0 mg/dl) and global ischemia (bilateral or solitary [single] kidney renal artery stenosis) There were 17 diabetic (DM) and 33 nondiabetic (NDM) patients. The endpoints included the follow-up measurements of renal function, blood pressure, and number of antihypertensive medications. Results: After stent placement, at a mean follow-up of 42 ± 18 months (range: 6–62 months), 79% NDM (N = 26), and 76% DM patients (N = 13) (P = NS) had improvement in the slope of the reciprocal of creatinine (1/SCr), indicating a beneficial effect in renal function in many patients. Conclusion: Renal artery stent placement appears to be equally beneficial in preserving renal function in DM and NDM patients with ischemic nephropathy and global renal ischemia. © 2006 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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