The impact of COVID-19 in diabetic kidney disease and chronic kidney disease: A population-based study
| Autor: | Maimoona Iftikhar, Antara Chatterjee, Juan Alonso Leon-Abarca, Roha Saeed Memon, Bahar Rehan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population Original Investigations/Commentaries law.invention Diabetic nephropathy symbols.namesake law Internal medicine Chronic Kidney Disease medicine Intubation Intratracheal Intubation Humans Diabetic Nephropathies Poisson regression Risk factor Renal Insufficiency Chronic education Mexico Aged education.field_of_study business.industry SARS-CoV-2 diabetic nephropathy COVID-19 Middle Aged medicine.disease Intensive care unit Hospitalization Pneumonia Intensive Care Units symbols Female business Kidney disease |
| Zdroj: | Acta Bio Medica : Atenei Parmensis |
| ISSN: | 2531-6745 0392-4203 |
| Popis: | BackgroundThe spectrum of pre-existing renal disease is known as a risk factor for severe COVID-19 outcomes. However, little is known about the impact of COVID-19 on patients with diabetic nephropathy in comparison to patients with chronic kidney disease.MethodsWe used the Mexican Open Registry of COVID-19 patients 11 to analyze anonymized records of those who had symptoms related to COVID-19 to analyze the rates of SARS-CoV-2 infection, development of COVID-19 pneumonia, admission, intubation, Intensive Care Unit admission and mortality. Robust Poisson regression was used to relate sex and age to each of the six outcomes and find adjusted prevalences and adjusted prevalence ratios. Also, binomial regression models were performed for those outcomes that had significant results to generate probability plots to perform a fine analysis of the results obtained along age as a continuous variable.ResultsThe adjusted prevalence analysis revealed that that there was a a 87.9% excess probability of developing COVID-19 pneumonia in patients with diabetic nephropathy, a 5% excess probability of being admitted, a 101.7% excess probability of intubation and a 20.8% excess probability of a fatal outcome due to COVID-19 pneumonia in comparison to CKD patients (p< 0.01).ConclusionsPatients with diabetic nephropathy had nearly a twofold rate of COVID-19 pneumonia, a higher probability of admission, a twofold probability of intubation and a higher chance of death once admitted compared to patients with chronic kidney disease alone. Also, both diseases had higher COVID-19 pneumonia rates, intubation rates and case-fatality rates compared to the overall population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|