Escherichia coli as a Multifaceted Pathogenic and Versatile Bacterium
| Autor: | Karine Melchior, Vânia Santos Braz, Cristiano G. Moreira |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Escherichia Microbiology (medical) Mini Review Highly pathogenic Microorganism 030106 microbiology Immunology lcsh:QR1-502 Virulence Context (language use) medicine.disease_cause Microbiology lcsh:Microbiology 03 medical and health sciences Cellular and Infection Microbiology Antibiotic resistance medicine Escherichia coli biology treatment genetic mobility multiresistant pathogenesis biology.organism_classification 030104 developmental biology Infectious Diseases Bacteria |
| Zdroj: | Frontiers in Cellular and Infection Microbiology, Vol 10 (2020) Frontiers in Cellular and Infection Microbiology |
| ISSN: | 2235-2988 |
| DOI: | 10.3389/fcimb.2020.548492 |
| Popis: | Genetic plasticity promotes evolution and a vast diversity in Escherichia coli varying from avirulent to highly pathogenic strains, including the emergence of virulent hybrid microorganism. This ability also contributes to the emergence of antimicrobial resistance. These hybrid pathogenic E. coli (HyPEC) are emergent threats, such as O104:H4 from the European outbreak in 2011, aggregative adherent bacteria with the potent Shiga-toxin. Here, we briefly revisited the details of these E. coli classic and hybrid pathogens, the increase in antimicrobial resistance in the context of a genetically empowered multifaceted and versatile bug and the growing need to advance alternative therapies to fight these infections. |
| Databáze: | OpenAIRE |
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