Co-infection of long-standing extensively drug-resistant Mycobacterium tuberculosis (XDR-TB) and non-tuberculosis mycobacteria: A case report
| Autor: | Mohammad H. Derakhshan, Amin Samiei, Kiarash Ghazvini, Nafiseh Izadi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Tuberculosis Capreomycin Case Report Drug resistance Microbiology Mycobacterium tuberculosis medicine XDR-TB lcsh:RC705-779 biology business.industry Isoniazid Cycloserine lcsh:Diseases of the respiratory system biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease bacterial infections and mycoses Virology Amikacin Ethionamide NTM business medicine.drug |
| Zdroj: | Respiratory Medicine Case Reports, Vol 15, Iss C, Pp 12-13 (2015) Respiratory Medicine Case Reports |
| ISSN: | 2213-0071 |
| DOI: | 10.1016/j.rmcr.2014.11.006 |
| Popis: | We report a 69-years-old Iranian HIV negative male patient, with long-standing pulmonary tuberculosis (eleven years) co-infected with non-tuberculosis mycobacteria. Despite of initiation of first line anti-tuberculosis therapy after diagnosis the patient poorly respond because of low compliance with anti-TB treatment. After several incomplete treatments the smear was still positive and thus drug susceptibility tests were performed on isolated organism which revealed that the organisms was resistant not only against isoniazid and rifampin but also against Ofloxacin (OFX), Capreomycin (CAP), p-aminosalicylic acid (PAS), ethionamide (ETH), Kanamycin (KAN), ciprofloxacin (Cip), amikacin (AMK) and cycloserine (CYC). Persistence and resistance of infection had led us to do more investigation using molecular methods, which revealed co-infection with Non-tuberculosis mycobacteria (NTM). The patient is still alive with cough and shortness of breath. |
| Databáze: | OpenAIRE |
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