Supplementary Figure S8 from PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer

Autor: Alvaro N. Monteiro, Uwe Rix, Eric B. Haura, Jhanelle E. Gray, Stephen G. Brantley, John M. Koomen, W. Douglas Cress, Elizabeth Remily-Wood, Jodi L. Kroeger, Fumi Kinose, Lily Rix, Gabriela Wright, Nicholas T. Woods, Ankita Jhuraney
Rok vydání: 2023
DOI: 10.1158/1535-7163.22507972
Popis: (A) TMA containing 68 patient-derived xenograft (PDX) tumor models stained with PAXIP1 and WEE1 (B-C) Two lung adenocarcinoma PDXs with PAXIP1 and WEE1 staining were used to perform ex vivo 3-D clonogenic assays with various concentrations of AZD1775 and cisplatin and tumor/control - T/C was measured by image analysis.
Databáze: OpenAIRE