Erectile haemodynamic status after radical prostatectomy correlates with erectile functional outcome
| Autor: | Michael Ohebshalom, Bedford W. Waters, Robert Flanagan, John P. Mulhall, Marilyn Parker |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Venous leak medicine.medical_specialty Duplex ultrasonography Phosphodiesterase Inhibitors Sildenafil Urology medicine.medical_treatment Hemodynamics Piperazines Sildenafil Citrate chemistry.chemical_compound Erectile Dysfunction Surveys and Questionnaires medicine Humans Prospective Studies Sulfones Prospective cohort study Prostatectomy Ultrasonography Doppler Duplex business.industry Penile Erection Prostatic Neoplasms Middle Aged Prognosis medicine.disease Comorbidity Surgery Treatment Outcome chemistry Patient Satisfaction Purines business Penis Radical retropubic prostatectomy |
| Zdroj: | BJU International. 102:592-596 |
| ISSN: | 1464-410X 1464-4096 |
| DOI: | 10.1111/j.1464-410x.2008.07695.x |
| Popis: | OBJECTIVE To define haemodynamic changes after radical retropubic prostatectomy (RP) and the predictive value of these for the outcome of erectile function (EF), as although there are predictors of the recovery of EF, penile vascular changes might also affect the recovery of EF. PATIENTS AND METHODS Prospective data were analysed from men who had RP followed by duplex penile Doppler ultrasonography (DUS) within 6 months of RP. All men had functional erections before RP, based on self-report and partner corroboration, and all completed the International Index of Erectile Function (IIEF) questionnaire serially after RP. The EF, based on IIEF scores, was then correlated with the penile DUS results. RESULTS In all, the study included 111 patients; 32 (29%) had normal erectile haemodynamics after RP, while 79 (71%) had abnormal haemodynamics. Twelve patients (11%) had a venous leak. There were no differences in mean patient age or comorbidity profile between those with and without haemodynamic changes. Comparing those with normal and abnormal haemodynamics, the mean IIEF EF domain scores were 25 and 17 (P = 0.025), the percentages of erectile rigidity at 18 months was 66% vs 35% (P = 0.013), the percentage of patients with normal EF domain scores was 28% vs 6% (P |
| Databáze: | OpenAIRE |
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