Thalamic afferents to prefrontal cortices from ventral motor nuclei in decision‐making
| Autor: | Marianela Garcia-Munoz, Bianca Sieveritz, Gordon W. Arbuthnott |
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| Rok vydání: | 2018 |
| Předmět: |
cognitive functions
Decision Making Prefrontal Cortex Ibags Special Issue Motor Activity Biology Somatosensory system Basal Ganglia action selection 03 medical and health sciences 0302 clinical medicine Mediodorsal thalamus Basal ganglia Animals Prefrontal cortex 030304 developmental biology Afferent Pathways Ventral Thalamic Nuclei 0303 health sciences Behavior Animal General Neuroscience Special Issue Review Associative learning Electrophysiology rodents Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | The European Journal of Neuroscience |
| ISSN: | 1460-9568 0953-816X |
| Popis: | The focus of this literature review is on the three interacting brain areas that participate in decision‐making: basal ganglia, ventral motor thalamic nuclei, and medial prefrontal cortex, with an emphasis on the participation of the ventromedial and ventral anterior motor thalamic nuclei in prefrontal cortical function. Apart from a defining input from the mediodorsal thalamus, the prefrontal cortex receives inputs from ventral motor thalamic nuclei that combine to mediate typical prefrontal functions such as associative learning, action selection, and decision‐making. Motor, somatosensory and medial prefrontal cortices are mainly contacted in layer 1 by the ventral motor thalamic nuclei and in layer 3 by thalamocortical input from mediodorsal thalamus. We will review anatomical, electrophysiological, and behavioral evidence for the proposed participation of ventral motor thalamic nuclei and medial prefrontal cortex in rat and mouse motor decision‐making. |
| Databáze: | OpenAIRE |
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