An intact urease assembly pathway is required to compete with NikR for nickel ions in Helicobacter pylori
| Autor: | Erin L. Benanti, Peter T. Chivers |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
chemistry.chemical_classification
Hydrogenase Urease Strain (chemistry) Helicobacter pylori Transcription Genetic Physiology and Metabolism Repressor Biology biology.organism_classification Microbiology Repressor Proteins Enzyme chemistry Biochemistry Bacterial Proteins Nickel biology.protein Nickel ions Molecular Biology Bacteria Gene Deletion |
| Zdroj: | Journal of bacteriology. 191(7) |
| ISSN: | 1098-5530 |
| Popis: | We examined the effects of urease and hydrogenase assembly gene deletions on NikR activation in H. pylori strains 26695 and G27. The loss of any component of urease assembly increased NikR activity under Ni 2+ -limiting conditions, as measured by reduced transcript levels and 63 Ni accumulation. Additionally, SlyD functioned in urease assembly in strain 26695. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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