Pressurized liquid extraction of six tetracyclines from agricultural soils
| Autor: | Matthew J. Morra, Sanjai J. Parikh, Inna E. Popova |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Liquid-Liquid Extraction
010501 environmental sciences 01 natural sciences Soil Limit of Detection Soil Pollutants Significant risk Chromatography High Pressure Liquid 0105 earth and related environmental sciences business.industry 010401 analytical chemistry Extraction (chemistry) Environmental engineering Veterinary Drugs Agriculture General Medicine Hydrogen-Ion Concentration Contamination Pollution Manure Anti-Bacterial Agents 0104 chemical sciences Accelerated solvent extraction Tetracyclines Soil water Environmental science business Groundwater Food Science |
| Zdroj: | Journal of Environmental Science and Health, Part B. 54:35-40 |
| ISSN: | 1532-4109 0360-1234 |
| DOI: | 10.1080/03601234.2018.1530547 |
| Popis: | Veterinary antibiotics used in agriculture can be introduced into the environment through land application of animal manure, accumulating in soils and groundwaters and posing a significant risk to human health and animal well-being. As the analysis of tetracyclines in soil is challenging due to their strong interaction with soil minerals and organic carbon, the objective of this study was to develop a reliable and reproducible method for quantitative analysis of chlortetracycline and oxytetracycline, and their respective metabolites in soils. A method based on pressurized liquid extraction (PLE) with in-cell clean-up was developed for the extraction of chlortetracycline and oxytetracycline and four likely metabolites from a set of four soils. Optimized conditions included a cell size of 22 mL, soil loading of 5 g, pH of 8.0, methanol:water ratio of 3:1, 50 °C, and two cycles. Soil extracts were analysed by high-performance liquid chromatography (HPLC) coupled with ion trap mass spectrometry (MS). Recoveries of seven tetracyclines from soil ranged from 41% to 110%. The limits of detection for tetracyclines were 0.08-0.3 µg g |
| Databáze: | OpenAIRE |
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