Prenatal diagnosis and outcome of unilateral multicystic kidney
| Autor: | Atıl Yüksel, Tayfun Oktar, Gürcan Türkyilmaz, Recep Has, Ibrahim Kalelioglu, Orhan Ziylan, Tuğba Saraç Sivrikoz, Emircan Erturk, Bilal Çetin |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Abnormal Karyotype Gestational Age Prenatal diagnosis Multicystic kidney Kidney Nephrectomy Ultrasonography Prenatal Pregnancy medicine Humans Multicystic Dysplastic Kidney business.industry Infant Newborn Obstetrics and Gynecology Gestational age Prognosis medicine.anatomical_structure Contralateral kidney Female Radiology Ultrasonography business |
| Zdroj: | Journal of Obstetrics and Gynaecology. 41:1071-1075 |
| ISSN: | 1364-6893 0144-3615 |
| Popis: | We reviewed the records of 144 patients. The mean gestational age at first US diagnosis was 27.5 ± 4.3 weeks. An anomaly of the contralateral kidney was detected in 25% of cases. An extrarenal anomaly was detected in 13.8%. Karyotype analysis was performed in 16.6% of cases and revealed trisomy 18 in 2 cases with extrarenal defects. Karyotype analysis was normal in all the patients who had isolated multicystic dysplastic kidney (MCDK). The diagnostic accuracy of prenatal ultrasound was 92.2%. Contralateral kidney anomaly was detected 33.9% of patients, and half of these were vesicoureteral reflux. Antihypertensive therapy was required in 2.6% of cases. Nephrectomy was performed in 8%, and partial or total involution of MCDK was achieved in 33.9% of patients. MCDK can be accurately diagnosed by prenatal sonography, and prognosis depends on extrarenal and contralateral renal abnormalities. In isolated cases, require of surgery is rare, and serial follow-up is suggested to determine involution.Impact statement |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|