Practicability of protontherapy using compact laser systems

Autor: Claude Albaret, Andre Antonetti, G. Grillon, Erik Lefebvre, Sven Fritzler, Emmanuel d'Humières, Victor Malka, Régis Ferrand, S. Meyroneinc, Jean-Paul Chambaret, Daniele Hulin
Přispěvatelé: Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Département de Physique Théorique et Appliquée (DPTA), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre de Protonthérapie d'Orsay (CPO), Centre de Protonthérapie d'Orsay
Rok vydání: 2004
Předmět:
numerical analysis
Proton
Physics::Medical Physics
Biophysics
Nanotechnology
radiation therapy
01 natural sciences
Biophysical Phenomena
Collimated light
laser applications in medicine
PACS 87.53.Bn
87.56.J
42.62.Be
010305 fluids & plasmas
law.invention
Radiotherapy
High-Energy

Acceleration
Optics
law
Neoplasms
0103 physical sciences
Proton Therapy
Humans
cancer
Computer Simulation
proton accelerators
Nuclear Experiment
010306 general physics
Laser beams
foils
[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics]
business.industry
High intensity
General Medicine
Laser
proton beams
Cancer treatment
[PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph]
Physics::Accelerator Physics
Laser Therapy
Radiotherapy
Conformal

business
Beam (structure)
Zdroj: Medical Physics
Medical Physics, American Association of Physicists in Medicine, 2004, 31 (6), pp.1587. ⟨10.1118/1.1747751⟩
Medical Physics, 2004, 31 (6), pp.1587. ⟨10.1118/1.1747751⟩
ISSN: 0094-2405
DOI: 10.1118/1.1747751
Popis: Protontherapy is a well-established approach to treat cancer due to the favorable ballistic properties of proton beams. Nevertheless, this treatment is today only possible with large scale accelerator facilities which are very difficult to install at existing hospitals. In this article we report on a new approach for proton acceleration up to energies within the therapeutic window between 60 and 200 MeV by using modern, high intensity and compact laser systems. By focusing such laser beams onto thin foils we obtained on target intensities of 6×10 19 W/cm 2 , which is sufficient to produce a well-collimated proton beam with an energy of up to 10 MeV. These results are in agreement with numerical simulations and indicate that proton energies within the therapeutic window should be obtained in the very near future using such economical and very compact laser systems. Hence, this approach could revolutionize cancer treatment by bringing the “lab to the hospital—rather than the hospital to the lab.”
Databáze: OpenAIRE