Practicability of protontherapy using compact laser systems
Autor: | Claude Albaret, Andre Antonetti, G. Grillon, Erik Lefebvre, Sven Fritzler, Emmanuel d'Humières, Victor Malka, Régis Ferrand, S. Meyroneinc, Jean-Paul Chambaret, Daniele Hulin |
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Přispěvatelé: | Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Département de Physique Théorique et Appliquée (DPTA), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre de Protonthérapie d'Orsay (CPO), Centre de Protonthérapie d'Orsay |
Rok vydání: | 2004 |
Předmět: |
numerical analysis
Proton Physics::Medical Physics Biophysics Nanotechnology radiation therapy 01 natural sciences Biophysical Phenomena Collimated light laser applications in medicine PACS 87.53.Bn 87.56.J 42.62.Be 010305 fluids & plasmas law.invention Radiotherapy High-Energy Acceleration Optics law Neoplasms 0103 physical sciences Proton Therapy Humans cancer Computer Simulation proton accelerators Nuclear Experiment 010306 general physics Laser beams foils [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics] business.industry High intensity General Medicine Laser proton beams Cancer treatment [PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph] Physics::Accelerator Physics Laser Therapy Radiotherapy Conformal business Beam (structure) |
Zdroj: | Medical Physics Medical Physics, American Association of Physicists in Medicine, 2004, 31 (6), pp.1587. ⟨10.1118/1.1747751⟩ Medical Physics, 2004, 31 (6), pp.1587. ⟨10.1118/1.1747751⟩ |
ISSN: | 0094-2405 |
DOI: | 10.1118/1.1747751 |
Popis: | Protontherapy is a well-established approach to treat cancer due to the favorable ballistic properties of proton beams. Nevertheless, this treatment is today only possible with large scale accelerator facilities which are very difficult to install at existing hospitals. In this article we report on a new approach for proton acceleration up to energies within the therapeutic window between 60 and 200 MeV by using modern, high intensity and compact laser systems. By focusing such laser beams onto thin foils we obtained on target intensities of 6×10 19 W/cm 2 , which is sufficient to produce a well-collimated proton beam with an energy of up to 10 MeV. These results are in agreement with numerical simulations and indicate that proton energies within the therapeutic window should be obtained in the very near future using such economical and very compact laser systems. Hence, this approach could revolutionize cancer treatment by bringing the “lab to the hospital—rather than the hospital to the lab.” |
Databáze: | OpenAIRE |
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