Intranigral injected iron progressively reduces striatal dopamine metabolism
| Autor: | M. Solbach, Wolfgang Wesemann, Peter Riederer, H.-W. Clement, Christoph Grote, S. Blaschke |
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| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty 3 4-Dihydroxyphenylacetic acid Dopamine Substantia nigra Striatum Biology Ferric Compounds Injections chemistry.chemical_compound Internal medicine Basal ganglia medicine Animals Rats Wistar Neurotransmitter Biological Psychiatry General Neuroscience Parkinson Disease Metabolism Corpus Striatum Rats Substantia Nigra Psychiatry and Mental health Endocrinology Neurology chemistry Catecholamine 3 4-Dihydroxyphenylacetic Acid Neurology (clinical) medicine.drug |
| Zdroj: | Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 8:209-214 |
| ISSN: | 1435-1463 0936-3076 |
| DOI: | 10.1007/bf02260941 |
| Popis: | The striatal dopamine metabolism of the rat was followed 1, 3, and 6 weeks after unilateral intranigral iron (III) (50- and 1.5 micrograms) application. For both concentrations a progredient decrease of extraneuronal 3.4-dihydroxyphenylacetic acid (DOPA) levels was observed in the ipsilateral striatum. |
| Databáze: | OpenAIRE |
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