Changes in the Serum Protein Composition in Mice with Transplanted Ehrlich’s Carcinoma
| Autor: | N. G. Kormosh, R. Kh. Ziganshin, F. V. Donenko, K. E. Voyushin, Victoria O. Shender |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Proteomics medicine.medical_specialty Serum protein Male mice Biology Mass Spectrometry General Biochemistry Genetics and Molecular Biology Mice Blood serum Internal medicine medicine Carcinoma Animals Electrophoresis Gel Two-Dimensional Tumor growth Carcinoma Ehrlich Tumor Crosses Genetic Blood Proteins General Medicine Allografts medicine.disease Mice Inbred C57BL Endocrinology Mice Inbred CBA Cancer research |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 158:489-492 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-015-2791-2 |
| Popis: | Injection of blood serum from mice with Ehrlich's carcinoma stimulates the growth of transplanted tumor, which proves the presence of tumor-specific factors in the serum. Experiments on (CBA×C57Bl/6)F1 male mice with transplanted Ehrlich's carcinoma demonstrated the appearance of new proteins in the serum, some of them are identified. The authors suggest continuing the search for tumor-associated factor by combining proteomic analytical methods and testing of identified candidate proteins for their effects on tumor growth. |
| Databáze: | OpenAIRE |
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