Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review

Autor: Muhammad Waqar Azeem, Afshan Naz Amray, Ahmed Waqas, Sadiq Naveed, Amna Mohyud Din Chaudhary
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Cureus
ISSN: 2168-8184
Popis: N-acetylcysteine (NAC) is a well-known antidote for acetaminophen toxicity and is easily available over the counter. It has antioxidant and anti-inflammatory properties and an established tolerance and safety profile. Owing to its neuroprotective effects, its clinical use has recently expanded to include the treatment of different psychiatric and non-psychiatric disorders. Although a number of randomized controlled trials have documented the clinical evidence for NAC, there are no reviews that summarize the evidence. The present scoping review summarizes the study designs, the patient characteristics, the evidence and the limitations in randomized controlled trials designed to explore the efficacy of NAC for psychiatric conditions in the pediatric population.
Databáze: OpenAIRE