Resolution of enuresis with aripiprazole in children with psychiatric disorders: two case reports

Autor:	Claudia Gliubizzi, Salvatore Mangano, Fulvio Guccione, Mariarita Capizzi, Rosaria Nardello, Antonio Marino
Přispěvatelé:	Rosaria Nardello, Fulvio Guccione, Claudia Gliubizzi, Antonio Marino, Mariarita Capizzi, Salvatore Mangano
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Autism Spectrum Disorder medicine.drug_class medicine.medical_treatment Aripiprazole Atypical antipsychotic Case Report Tourette syndrome 03 medical and health sciences 0302 clinical medicine Enuresis mental disorders medicine Humans Bipolar disorder Child Psychiatry Antipsychotic business.industry General Medicine medicine.disease 030227 psychiatry Schizophrenia Medicine Female medicine.symptom business Mania 030217 neurology & neurosurgery Antipsychotic Agents Nocturnal Enuresis medicine.drug
Zdroj:	Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-3 (2021) Journal of Medical Case Reports
ISSN:	1752-1947
Popis:	Background Aripiprazole is a third-generation atypical antipsychotic drug that acts as a stabilizer of the dopaminergic and serotonergic system. As partial agonist of the dopamine (D2) and serotonin (5-HT1A) receptors, it appears to be effective in reducing mania in patients with bipolar disorder, tics in Tourette Syndrome, aggression in schizophrenia and autism spectrum disorder. Enuresis has been reported among its side effects. Only a few studies, with conflicting results, have investigated the relationship between aripiprazole and enuresis. Case presentation We report the disappearance of enuresis in a Caucasian girl with intellectual disability and oppositional defiant disorder and in a Caucasian boy with intellectual disability and early-onset psychosis, both following initiation of treatment with aripiprazole. Conclusion The aim of this study was to contribute to the literature on the use of aripripazole in subjects with enuresis. Our findings lead us to suggest that aripiprazole is less burdened with side effects, including bedwetting, than other antipsychotic drugs.
Databáze:	OpenAIRE
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