Treatment of high-dose intrathecal morphine overdose. Case report
| Autor: | Stephen M. Bloomfield, Sandi Cline, Daniel Banks, Howard H. Kaufman, Kent Sauter |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Nitroprusside
medicine.medical_specialty medicine.medical_treatment Status epilepticus Cerebrospinal fluid Status Epilepticus Naloxone medicine Humans Infusion Pumps Injections Spinal Intracerebral hemorrhage Chemotherapy Morphine Narcotic antagonist business.industry Middle Aged medicine.disease Surgery Respiratory failure Anesthesia Phenytoin Female medicine.symptom Drug Overdose business medicine.drug |
| Zdroj: | Journal of neurosurgery. 81(1) |
| ISSN: | 0022-3085 |
| Popis: | ✓ The case is reported of a 45-year-old woman who was being treated for chronic back and right leg pain with intrathecal morphine administered via a subcutaneous continuous-infusion device. She received an accidental 450-mg bolus injection of morphine intrathecally and developed hypertension, status epilepticus, intracerebral hemorrhage, and respiratory failure. Treatment with continuous intravenous naloxone infusion, lumbar catheter drainage of cerebrospinal fluid, and control of hypertension and status epilepticus resulted in an excellent outcome with return to neurological baseline. Care providers who refill pump reservoirs with morphine must be knowledgeable about these devices and the life-threatening consequences associated with errors in refilling them. This case describes the complications and successful treatment of high-dose intrathecal morphine overdose. |
| Databáze: | OpenAIRE |
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