Prevalence of osteoporosis and factors affecting bone mineral density among postmenopausal Turkish women with type 2 diabetes
| Autor: | Melek Eda Ertorer, Asli Nar-Demirer, Neslihan Bascil-Tutuncu, Inan Anaforoglu |
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| Rok vydání: | 2007 |
| Předmět: |
musculoskeletal diseases
Adult medicine.medical_specialty Bone density Turkey Endocrinology Diabetes and Metabolism Osteoporosis Type 2 diabetes Bone remodeling Endocrinology Bone Density Internal medicine Diabetes mellitus Internal Medicine medicine Prevalence Humans Osteoporosis Postmenopausal Femoral neck Aged Bone mineral Aged 80 and over business.industry Middle Aged medicine.disease Osteopenia Bone Diseases Metabolic medicine.anatomical_structure Diabetes Mellitus Type 2 Female business |
| Zdroj: | Journal of diabetes and its complications. 23(1) |
| ISSN: | 1873-460X |
| Popis: | Objectives Controversy remains as to the effects of type 2 diabetes on bone metabolism. The aims of this study were to assess the association between type 2 diabetes and bone mineral density (BMD) and to evaluate the possible relationship between chronic diabetic complications and bone density. Methods Bone mineral densities at the lumbar spine, femur, and radius in 206 postmenopausal Turkish women with type 2 diabetes were evaluated by dual-energy X-ray absorptiometry and compared with those in 61 age-matched postmenopausal nondiabetic women. Medical and lifestyle characteristics, body mass index (BMI), hemoglobin A 1c level, and status of microvascular and macrovascular diabetic complications were recorded. Frequency of osteoporosis and that of osteopenia as well as the relationship between microvascular and macrovascular complications and BMD were evaluated. Results The groups did not differ on BMDs and T scores at the hip, lumbar spine, and radius. Patients with radial and/or lumbar and/or hip osteoporosis had a longer duration of diabetes ( P =.000), were older ( P =.000), and had a lower BMI ( P =.000). No correlation was found between osteopenia or osteoporosis and hemoglobin A 1c level, presence of microalbuminuria, retinopathy, neuropathy, peripheral artery disease, cerebrovascular event, and coronary artery disease. Among the three sites, BMD at the hip was positively correlated with BMI ( P =.000) but negatively correlated with age ( P =.000) and duration of diabetes ( P =.000). Presence of microalbuminuria revealed a negative correlation with BMD at the femoral neck ( P =.042). Conclusion There is no evidence that type 2 diabetes influenced BMD in our postmenopausal patient group. |
| Databáze: | OpenAIRE |
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