STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF LAMELLAR MACULAR HOLES
| Autor: | Justin Nguyen, Kenneth M.P. Yee, J Sebag, Jeannie Nguyen-Cuu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Visual acuity genetic structures media_common.quotation_subject Tangential traction Visual Acuity Optic disk Spectral domain Contrast Sensitivity 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ophthalmology Humans Medicine Contrast (vision) Macula Lutea Aged Retrospective Studies 030304 developmental biology media_common 0303 health sciences Amsler grid business.industry Retinal General Medicine Prognosis Retinal Perforations eye diseases Cross-Sectional Studies chemistry Visual function 030221 ophthalmology & optometry Female sense organs medicine.symptom business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Retina. 39:2084-2089 |
| ISSN: | 0275-004X |
| DOI: | 10.1097/iae.0000000000002275 |
| Popis: | Purpose Lamellar macular holes (LMHs) can been subdivided into tractional and degenerative subtypes. This cross-sectional cohort study compared structural and functional characteristics in these subtypes hypothesizing that tractional LMH has a higher prevalence of vitreopapillary adhesion and tangential traction (macular pucker), whereas degenerative LMH has more ellipsoid zone disruption and worse vision, measured three different ways. Methods Tractional LMH (n = 22) and degenerative LMH (n = 15) were distinguished by optical coherence tomography criteria. Separate spectral domain optical coherence tomography scanning of the macula and optic disk was performed. Visual acuity, contrast sensitivity function (Weber Index, %W), and the degree of visual distortions (3-dimensional threshold Amsler grid; % volume lost [%VL]) were quantified. Results Vitreopapillary adhesion was present in 14/22 (64%) tractional, but in only 3/15 (20%) degenerative LMH (P = 0.006). Macular pucker was present in 19/22 (86%) tractional, but in only 8/15 (53%) degenerative LMH (P = 0.011). Ellipsoid zone disruption was present in 13/15 (87%) degenerative, but in only 2/22 (9%) tractional LMH (P = 0.0001). Visual acuity was better in tractional than degenerative LMH (P = 0.006), as was contrast sensitivity function (tractional = 3.44 ± 1.07 %W, degenerative = 4.66 ± 1.73 %W; P = 0.015). Visual distortions were less in tractional (0.33 ± 0.61 %VL) than in degenerative (0.85 ± 0.68 %VL) LMH (P = 0.014). Conclusion Structure and visual function differ significantly in subtypes of LMH. Tractional LMH has 3-fold higher prevalence of vitreopapillary adhesion and 2-fold higher prevalence of macular pucker. Degenerative LMH has 9-fold more ellipsoid zone disruption, worse visual acuity and contrast sensitivity function, and 3-fold more distortions. Thus, outer retinal integrity seems more closely correlated with vision than anterior structural abnormalities in LMH. |
| Databáze: | OpenAIRE |
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