Doppler screening and predictors of adverse outcomes in high risk pregnancies affected by tobacco
| Autor: | Byron C Calhoun, Mike Broce, Dara J Seybold, Alison Stalzer, Deena Hossino |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pregnancy High-Risk Population Diastole 030204 cardiovascular system & hematology Toxicology Ultrasonography Prenatal Umbilical Arteries Preeclampsia 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Pregnancy Humans Medicine education Retrospective Studies education.field_of_study 030219 obstetrics & reproductive medicine Receiver operating characteristic business.industry Obstetrics Smoking Pregnancy Outcome Ultrasonography Doppler Retrospective cohort study Stepwise regression medicine.disease Confidence interval Pregnancy Complications Uterine Artery Low birth weight Female medicine.symptom business |
| Zdroj: | Reproductive Toxicology. 67:10-14 |
| ISSN: | 0890-6238 |
| DOI: | 10.1016/j.reprotox.2016.11.006 |
| Popis: | The purpose of this study was to investigate associations between Doppler measurements and adverse outcomes in an obstetric population with high tobacco use.This retrospective study included patients with Doppler data (umbilical systolic/diastolic velocity ratios (S/D), uterine S/D, uterine left/right ratio index (RI)). Receiver operator characteristic curve analysis determined cut-off elevated Doppler indices. Stepwise logistic regression was used to predict adverse outcomes.338 of 745 patients (45.4%) had adverse outcomes. Doppler artery indices identified significant associations with IUGR, preeclampsia, low birth weight, pre-term birth and composite adverse outcome variable. An elevated Umbilical S/D was 2.1 (95% Confidence Interval (CI): 1.5-2.9; p0.001) times was more likely to have an adverse outcome. For left uterine artery S/D and nulliparity, the odds ratios were 1.8 (95% CI: 1.3-2.5) and 1.4 (95% CI: 1.0-1.9), respectively.Umbilical and uterine left S/D indices and nulliparity are significant independent predictors of adverse outcomes. |
| Databáze: | OpenAIRE |
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