Management and treatment of hepatitis B virus in patients with HIV infection: A practical guide for health care professionals

Autor: Rachel Therrien, Annie Talbot, Marc-André Charron, Jean-Pierre Villeneuve, Marc Poliquin, Jean-Guy Baril, Cécile Tremblay, Claude Fortin, Richard N. Lalonde, Marina B. Klein, Benoit Trottier, Irina Tsarevsky, Marie-France Matte
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 22, Iss 3, Pp 88-96 (2011)
Popis: The management and treatment of HIV and hepatitis B virus (HBV)-coinfected patients present specific challenges for clinicians. The morbidity and mortality related to these concomitant infections are growing concerns, while the use of antiviral drugs effective against both viruses complicates therapeutic decision making. The present document provides guidelines for physicians regarding care and treatment of patients coinfected with HIV and HBV. Primary prevention of HBV in HIV-positive patients is achieved through appropriate vaccination schedules. Follow-up before treatment of HBV may include liver biopsy, screening for hepatocellular carcinoma and testing for esophageal varicies in cases of cirrhosis. In HBV-infected patients requiring treatment, recommendations regarding initiation, duration and choice of first-line drugs are made. Finally, in the case of resistance, appropriate alternative therapies are necessary.
Databáze: OpenAIRE