Radio-protective role of antioxidant agents
| Autor: | Mehran Mohseni, Alireza Shirazi, Ehsan Mihandoost, Seied Rabie Mahdavi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Cancer Research
lcsh:Internal medicine Antioxidant medicine.medical_treatment radio-protectors herbal radio-protectors Review vitamin E Pharmacology Ionizing radiation Toxicology Melatonin chemistry.chemical_compound Therapeutic index medicine lcsh:RC31-1245 Reactive nitrogen species chemistry.chemical_classification Reactive oxygen species business.industry Vitamin E lcsh:Other systems of medicine lcsh:RZ201-999 melatonin antioxidants chemistry Oncology Toxicity business medicine.drug |
| Zdroj: | Oncology Reviews, Vol 6, Iss 2 (2012) Oncology Reviews |
| ISSN: | 1970-5565 1970-5557 |
| Popis: | Ionizing radiation interacts with biological systems to produce reactive oxygen species and reactive nitrogen species which attack various cellular components. Radio-protectors act as prophylactic agents to shield healthy cells and tissues from the harmful effects of radiation. Past research on synthetic radio-protectors has brought little success, primarily due to the various toxicity-related problems. Results of experimental research show that antioxidant nutrients, such as vitamin E and herbal products and melatonin, are protective against the damaging effects of radiation, with less toxicity and side effects. Therefore, we propose that in the future, antioxidant radio-protective agents may improve the therapeutic index in radiation oncology treatments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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